代表性论文：

1.  Xu C, Qin D, Lu X, Qi Q, Wu Y, Wang Q, Han Z, Nie X, Jiang Y, Deng D*, Xie W*, Gao Z*, Li L*. Subcortical maternal complex safeguards H3K4me3 reprogramming and ZGA by preventing SPIN1’s nuclear entry in mouse early embryos. Nature Structural & Molecular Biology. 2025 Aug;32(8):1358-1372. doi: 10.1038/s41594-025-01538-0.
2.  Han Z, Wang R, Chi P, Zhang Z, Jiao H, Ou G, Qin D, Xu C, Gao Z, Qi Q, Li J, Wang X, Chen J, Hu H, Li L*, Deng D*. The subcortical maternal complex modulates the cell cycle of mouse early embryogenesis through 14-3-3. Nature Communications. 2024 Oct 15;15(1):8887. doi: 10.1038/s41467-024-53277-3.
3.  Chi P, Ou G, Qin D, Han Z, Li J, Xiao Q, Gao Z, Xu C, Qi Q, Liu Q, Liu S, Li J, Guo L, Lu Y, Chen J, Wang X, Shi H, Li L^*, Deng D^*. Structural basis of subcortical maternal complex and its implications in reproduction disorders. Nature Structural & Molecular Biology. 2024 Jan;31(1):115-124.
4.  Nie X, Xu Q, Xu C, Chen F, Wang Q, Qin D, Wang R, Gao Z, Lu X, Yang X, Wu Y, Gu C, Xie W^*, Li L^*. Maternal TDP-43 interacts with RNA Pol II and regulates zygotic genome activation. Nature Communications. 2023 Jul 17;14(1):4275.
5.  Quan Y, Wang M, Xu C, Wang X, Qin D, Lin Y, Lu X, Lu F^*, Li L^*. Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition. Nucleic Acids Research. 2022 May 6;50(8):4414-4435.
6.  Xiong Z, Xu K, Lin Z, Kong F, Wang Q, Quan Y, Sha Q, Li F, Zou Z, Liu L, Ji S, Chen Y, Zhang H, Fang J, Yu G, Liu B, Wang L, Wang H, Deng H, Yang X, Fan H, Li L^*, Xie W^*. Ultrasensitive Ribo-seq reveals translational landscapes during oocyte-to-embryo transition and early development. Nature Cell Biology. 2022 Jun;24(6):968-980.
7.  Wang X, Xiang Y, Yu Y, Wang R, Zhang Y, Xu Q, Sun H, Zhao Z, Jiang X, Wang X, Lu X, Qin D, Quan Y, Zhang J, Shyh-Chang N, Wang H, Jing N, Xie W^*, Li L^*. Formative pluripotent stem cells show features of epiblast cells poised for gastrulation. Cell Research. 2021 May; 31(5): 526-541.
8.  Ma H, Zhai J, Wan H, Jiang X, Wang X, Wang L, Xiang Y, He X, Zhao Z, Zhao B, Zheng P^*, Li L^*, Wang H^*. In vitro culture of cynomolgus monkey embryos beyond early gastrulation. Science. 2019 Nov 15; 366 (6467): eaax7890.
9.  Qin D, Gao Z, Xiao Y, Zhang X, Ma H, Yu X, Nie X, Fan N, Wang X, OuYang Y, Sun Q, Yi Z, Li L^*. The subcortical maternal complex protein Nlrp4f is involved in cytoplasmic lattice formation and organelle distribution. Development. 2019 Oct;146(20):dev183616.
10.  Gao Z, Zhang X, Yu X, Qin D, Yu Y, Liu W, Xiang Y, Xiao Y, Lu X, Yi Z, Li L*. ZBED3 participates in the subcortical maternal complex and regulates the distribution of organelles. Journal of Molecular Cell Biology. 2018 Feb; 10(1): 74-88.
11.  Liu W, Wang F, Xu Q, Shi J, Zhang X, Lu X, Gao Z, Ma H, Zhao Z, Duan E, Gao F, Gao S^*, Yi Z^*, Li L^*. BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis. Nature Communications. 2017 Jan 27; 8:14182.
12.  Lu X, Gao Z, Qin D, Li L*. A maternal functional module in the mammalian oocyte-to-embryo transition. Trends in Molecular Medicine. 2017 Nov; 23 (11) 1014–1023.
13.  Zhu K, Yan L, Zhang X, Lu X, Wang T, Yan J, Liu X, Qiao J*, Li L*. Identification of a human subcortical maternal complex. Molecular Human Reproduction. 2015 Apr; 21(4): 320-9.
14.  Yu X, Yi Z, Gao Z, Qin D, Zhai Y, Chen X, Ou-Yang Y, Wang Z, Zheng P, Zhu M, Wang H, Sun QY, Dean J^*, Li L^*. The subcortical maternal complex controls symmetric division of mouse zygotes by regulating F-actin dynamics. Nature Communications. 2014 Sep 11; 5:4887.
15.  Li L^*, Baibakov B and Dean J. A subcortical maternal complex essential for pre-implantation mouse embryogenesis. Developmental Cell. 2008 Sep; 15(3): 416-25

代表性专利：

1. 活化态多能干细胞及其制备方法和应用。ACTIVATED PLURIPOTENT STEM CELL, AND PREPARATION METHOD THEREFOR AND USE THEREOF（AU2021350981B9; Australia）